SCHEMBL627794

SCHEMBL627794

CCCC(C)C(C)(C)c1cc(C)cc(=O)n1O

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 17/20 0.39
NR1I2 O75469 1/20 0.34
KDM4B O94953 1/20 0.34
CHRM1 P11229 1/20 0.34
TBXA2R P21731 1/20 0.34
ADRA1A P35348 1/20 0.34
DOHH Q9BU89 1/20 0.34
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
CYP1A2 P05177 1/20 0.32
ALOX12 P18054 1/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HIF1A Q16665 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6276567 0.73 IDH1 (0.41) IDH1NR1I2KDM4BCHRM1TBXA2R
SCHEMBL21762069 0.68 IDH1 (0.42) IDH1NR1I2KDM4BCHRM1TBXA2R
SCHEMBL5409295 0.67 SHMT2 (0.35) SMN1; SMN2
SCHEMBL29020334 0.67 CA1 (0.39) KDM4EMAPK1SMN1; SMN2
SCHEMBL7087619 0.63 IDH1 (0.46) IDH1NR1I2KDM4BCHRM1TBXA2R
SCHEMBL7089306 0.63 IDH1 (0.65) IDH1
Piroctone SCHEMBL28331516 0.63 IDH1 (0.47) IDH1
Piroctone SCHEMBL3588 0.63 IDH1 (0.50) IDH1
SCHEMBL6941621 0.63 IDH1 (0.54) IDH1
Piroctone SCHEMBL7568492 0.63 IDH1 (0.50) IDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118202009-A Ink applicator 墨水盒墨水公司 2024-06-14 CN claimed
CN-117462451-B Antifungal agent-containing composition and preparation and application thereof 拉芳家化股份有限公司 2024-04-02 CN claimed
CN-117462451-A Antifungal agent-containing composition and preparation and application thereof 拉芳家化股份有限公司 2024-01-30 CN claimed
US-20230218641-A1 ANTI-ACNE COMPOSITIONS L'OREAL (FR) 2023-07-13 US claimed
CN-116267961-A Mildew-proof method for natural rubber 中国化工集团曙光橡胶工业研究设计院有限公司 2023-06-23 CN claimed
CN-116322621-A Semi-permanent tattoo 墨水盒墨水公司 2023-06-23 CN claimed
CN-115996980-A Semi-permanent tattoo 墨水盒墨水公司 2023-04-21 CN claimed
CN-115916147-A Anti-acne composition 欧莱雅 2023-04-04 CN claimed
EP-4153127-A1 ANTI-ACNE COMPOSITIONS L'OREAL (FR) 2023-03-29 EP claimed
CN-115784981-A Preparation process of piroctone olamine salt 宿迁旭升化工有限公司 2023-03-14 CN claimed
CN-108430443-B Cosmetic composition comprising anionic surfactant, at least 3.5% by weight of fatty acid and antidandruff agent 欧莱雅 2023-01-03 CN claimed
WO-2021234014-A1 ANTI-ACNE COMPOSITIONS L'OREAL (FR) 2021-11-25 WO claimed
US-20080119527-A1 Composition for combating the localized hyperpigmentation of dark skin L'OREAL (FR) 2008-05-22 US claimed
EP-1900353-A1 Composition to combat localised hyperpigmentation in dark skin types L'OREAL (FR) 2008-03-19 EP claimed
EP-0865278-A1 USE OF 1-HYDROXY-2-PYRIDONES FOR TREATING MUCOSA DISEASES WHICH ARE DIFFICULT TO TREAT HOECHST AKTIENGESELLSCHAFT (DE) 1998-09-23 EP claimed
WO-1997020560-A1 USE OF 1-HYDROXY-2-PYRIDONES FOR TREATING MUCOSA DISEASES WHICH ARE DIFFICULT TO TREAT HOECHST AKTIENGESELLSCHAFT (DE) 1997-06-12 WO claimed
EP-4739279-A1 RED ALGAE BIOMASS EXTRACT, AND COSMETIC USE THEREOF FOR ELIMINATING SKIN IMPERFECTIONS Fermentalg (FR) 2026-05-13 EP disclosed
WO-2025012135-A1 RED ALGAE BIOMASS EXTRACT, AND COSMETIC USE THEREOF FOR ELIMINATING SKIN IMPERFECTIONS FERMENTALG (FR) 2025-01-16 WO disclosed
EP-1064916-A1 Cosmetic compositions containing an amphoteric polymer and an anti-dandruff agent and their uses L'OREAL (FR) 2001-01-03 EP disclosed
US-6162834-A Foaming oil-in-water emulsion based on nonionic surfactants, a fatty phase and a crosslinked cationic or anionic polymer, and its use in topical applications L'OREAL (FR) 2000-12-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230218641-A1 ANTI-ACNE COMPOSITIONS CUTA, EBP, ACMSD IDH1 4129/4885NR1I2 3471/4885KDM4B 3866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.