SCHEMBL5409295

SCHEMBL5409295

CCCC(C)C(C)(C)c1cc(C)cc(=O)[nH]1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SHMT2 P34897 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
PKM P14618 1/20 0.34
HTT P42858 1/20 0.34
HSD17B10 Q99714 1/20 0.34
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.31
GPR84 Q9NQS5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29016899 0.81 MAPT (0.30) MAPT
SCHEMBL1170468 0.81 PRKCA (0.34) SHMT2GAAGPR84
SCHEMBL15059436 0.76 GPR84 (0.38) HSD17B10GAAGPR84
SCHEMBL2471001 0.75 SHMT2 (0.33) SHMT2SMN1; SMN2PKMHTTHSD17B10
SCHEMBL18701493 0.72 CA1 (0.43) SMN1; SMN2HSD17B10GAAMAPTGPR84
SCHEMBL29020334 0.69 CA1 (0.39) SMN1; SMN2HTTHSD17B10GAAMAPT
SCHEMBL627794 0.67 IDH1 (0.39) SMN1; SMN2
SCHEMBL20618567 0.67 GPR84 (0.35) SHMT2GAAGPR84
SCHEMBL6126623 0.66 KDM4E (0.47) SMN1; SMN2HTTHSD17B10
SCHEMBL5352433 0.66 GAA (0.33) GAAGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7186045-B2 Device and method for applying a cosmetic product L'OREAL S.A. (FR) 2007-03-06 US disclosed
US-20040247373-A1 Device and method for applying a cosmetic product L'OREAL (FR) 2004-12-09 US disclosed
US-20010031168-A1 Packaging and applicator device including a porous structure incorporating a biocidal agent L'OREAL S.A. (FR) 2001-10-18 US disclosed