Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PDE6D | O43924 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RGS12 | O14924 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29020532 | 0.86 | GAA (0.41) | L3MBTL1MAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL29020552 | 0.85 | NPC1 (0.56) | L3MBTL1MAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL29020542 | 0.77 | MEN1 (0.59) | MAPTNPC1ALDH1A1RAB9ALMNA | |
| SCHEMBL30498869 | 0.77 | MEN1 (0.44) | L3MBTL1MAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL29020549 | 0.77 | PDE6D (0.51) | ALDH1A1GAAHTTNPSR1LMNA | |
| SCHEMBL29020528 | 0.72 | KMT2A (0.57) | MAPTNPC1RAB9ALMNAMEN1 | |
| SCHEMBL19281523 | 0.71 | PTGS2 (0.49) | L3MBTL1MAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL5330985 | 0.69 | TSHR (0.56) | L3MBTL1MAPTALDH1A1GAALMNA | |
| SCHEMBL29020522 | 0.67 | MAPT (0.64) | L3MBTL1MAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL29020524 | 0.66 | NPC1 (0.58) | MAPTNPC1ALDH1A1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113402473-B | Thiotriazole compound, preparation method and application thereof | 四川省医学科学院·四川省人民医院 | 2023-06-23 | — | — | CN | disclosed |
| CN-113402473-A | Thiotriazole compound, preparation method and application thereof | 四川省医学科学院·四川省人民医院 | 2021-09-17 | — | — | CN | disclosed |