Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | BAP1 | Q92560 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5329766 | 0.90 | GAA (0.64) | TSHRGAAADRB2MEN1KMT2A | |
| SCHEMBL5422195 | 0.89 | GAA (0.62) | TSHRGAAADRB2MEN1KMT2A | |
| SCHEMBL5338355 | 0.87 | TSHR (0.59) | TSHRGAAADRB2MEN1KMT2A | |
| SCHEMBL5332827 | 0.84 | GAA (0.56) | TSHRGAAADRB2MEN1KMT2A | |
| SCHEMBL5336137 | 0.81 | KMT2A (0.62) | TSHRGAAADRB2MEN1KMT2A | |
| SCHEMBL5336129 | 0.81 | KMT2A (0.62) | TSHRGAAADRB2MEN1KMT2A | |
| SCHEMBL5336800 | 0.80 | KMT2A (0.80) | TSHRGAAADRB2MEN1KMT2A | |
| SCHEMBL5329256 | 0.80 | ALDH1A1 (0.58) | TSHRGAAADRB2MEN1KMT2A | |
| SCHEMBL5425561 | 0.77 | RXFP1 (0.60) | TSHRGAAADRB2MEN1KMT2A | |
| SCHEMBL5416217 | 0.77 | ALDH1A1 (0.60) | TSHRGAAADRB2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047394-A2 | THIOTRIAZOLYL DERIVATIVES | EPIX DELAWARE, INC. (US) | 2007-04-26 | — | — | WO | disclosed |