Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.55 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL903704 | 0.88 | SIGMAR1 (0.63) | SIGMAR1TAAR1SLC18A2CYP3A4TSHR | |
| SCHEMBL970741 | 0.82 | TAAR1 (0.66) | SIGMAR1TAAR1SLC18A2CYP3A4TSHR | |
| SCHEMBL3905889 | 0.82 | SIGMAR1 (0.54) | SIGMAR1TAAR1SLC18A2CYP3A4TSHR | |
| SCHEMBL9320616 | 0.82 | SIGMAR1 (0.53) | SIGMAR1TAAR1SLC18A2CYP3A4TSHR | |
| SCHEMBL431573 | 0.80 | HTT (0.50) | HTTCYP3A4ALDH1A1ALOX12MAPK1 | |
| SCHEMBL5536511 | 0.80 | SIGMAR1 (0.53) | SIGMAR1TAAR1SLC18A2CYP3A4TSHR | |
| SCHEMBL10725182 | 0.80 | TAAR1 (0.56) | SIGMAR1TAAR1SLC18A2CYP3A4TSHR | |
| SCHEMBL3748719 | 0.80 | TDP1 (0.52) | SIGMAR1TAAR1SLC18A2CYP3A4TSHR | |
| SCHEMBL5010083 | 0.77 | SIGMAR1 (0.46) | SIGMAR1TAAR1SLC18A2CYP3A4TSHR | |
| SCHEMBL8092729 | 0.76 | SIGMAR1 (0.82) | SIGMAR1TAAR1SLC18A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117752782-A | Subcutaneous HER2 antibody formulations | 豪夫迈·罗氏有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-117180422-A | Adjuvant therapy of HER2 positive breast cancer | 豪夫迈·罗氏有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-110167594-B | Subcutaneous HER2 antibody formulations | 豪夫迈·罗氏有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-117018187-A | Use of the HER2 dimerization inhibitor pertuzumab and articles of manufacture comprising the HER2 dimerization inhibitor pertuzumab | 霍夫曼-拉罗奇有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-116271011-B | Use of the HER2 dimerization inhibitor pertuzumab and articles of manufacture comprising the HER2 dimerization inhibitor pertuzumab | 霍夫曼-拉罗奇有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116850283-A | Adjuvant therapy of HER2 positive breast cancer | 豪夫迈·罗氏有限公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-116808199-A | Use of the HER2 dimerization inhibitor pertuzumab and articles of manufacture comprising the HER2 dimerization inhibitor pertuzumab | 霍夫曼-拉罗奇有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-116531511-A | Adjuvant therapy of HER2 positive breast cancer | 豪夫迈·罗氏有限公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-110337450-B | Adjuvant therapy of HER2 positive breast cancer | 豪夫迈·罗氏有限公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-109908341-B | Use of the HER2 dimerization inhibitor pertuzumab and articles of manufacture comprising the HER2 dimerization inhibitor pertuzumab | 霍夫曼-拉罗奇有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-116271013-A | Use of the HER2 dimerization inhibitor pertuzumab and articles of manufacture comprising the HER2 dimerization inhibitor pertuzumab | 霍夫曼-拉罗奇有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116271011-A | Use of the HER2 dimerization inhibitor pertuzumab and articles of manufacture comprising the HER2 dimerization inhibitor pertuzumab | 霍夫曼-拉罗奇有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116236569-A | Use of the HER2 dimerization inhibitor pertuzumab and articles of manufacture comprising the HER2 dimerization inhibitor pertuzumab | 霍夫曼-拉罗奇有限公司 | 2023-06-09 | — | — | CN | disclosed |