Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 13/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.49 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL903704 | 0.82 | SIGMAR1 (0.63) | TDP1SIGMAR1TAAR1SLC18A2NPC1 | |
| SCHEMBL970741 | 0.80 | TAAR1 (0.66) | SIGMAR1TAAR1SLC18A2ALDH1A1CYP3A4 | |
| SCHEMBL29020992 | 0.80 | SIGMAR1 (0.55) | SIGMAR1TAAR1SLC18A2NPC1RAB9A | |
| SCHEMBL12871153 | 0.77 | TDP1 (0.46) | TDP1NPC1RAB9AACACBALDH1A1 | |
| SCHEMBL3905889 | 0.77 | SIGMAR1 (0.54) | SIGMAR1TAAR1SLC18A2NPC1RAB9A | |
| SCHEMBL9320616 | 0.77 | SIGMAR1 (0.53) | SIGMAR1TAAR1SLC18A2ALDH1A1CYP3A4 | |
| SCHEMBL3748016 | 0.75 | THRB (0.46) | SIGMAR1TAAR1NPC1RAB9AACACB | |
| SCHEMBL31443251 | 0.75 | ALDH1A1 (0.50) | TDP1SIGMAR1TAAR1SLC18A2ACACB | |
| SCHEMBL31443252 | 0.75 | SIGMAR1 (0.56) | TDP1SIGMAR1TAAR1SLC18A2NPC1 | |
| SCHEMBL5536511 | 0.75 | SIGMAR1 (0.53) | SIGMAR1TAAR1SLC18A2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7838188-B2 | Electrophotographic photoconductor, image forming method, image forming apparatus, and process cartridge | RICOH COMPANY, LTD. (JP) | 2010-11-23 | — | — | US | disclosed |
| US-20070231720-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE | RICOH COMPANY, LTD. (JP) | 2007-10-04 | — | — | US | disclosed |