SCHEMBL29021085

SCHEMBL29021085

C=CCC(C)(OC(N)=O)C(C)C

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.34
HTT P42858 1/20 0.33
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA4 P43681 1/20 0.32
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP3 P08254 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7023420 0.78 HTT (0.35) HTTTSHR
SCHEMBL11602378 0.78 HTT (0.35) HTTTSHR
SCHEMBL28694555 0.73 HTT (0.33) HTT
SCHEMBL8850951 0.72 HTT (0.32) HTTMMP1
SCHEMBL15302126 0.71
SCHEMBL1369031 0.70
SCHEMBL1371202 0.70
Allylamine SCHEMBL4894416 0.69 ALDH1A1 (0.39) TSHR
SCHEMBL11032795 0.69 HTT (0.35) HTTTSHR
SCHEMBL29742734 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116323638-A Stapled peptides and methods thereof 弗格制药有限公司 2023-06-23 CN disclosed