Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9341680 | 0.80 | ALDH1A1 (0.42) | ALDH1A1TSHRFGFR4 | |
| SCHEMBL11602378 | 0.74 | HTT (0.35) | HTTALDH1A1TSHRFGFR4 | |
| SCHEMBL7023420 | 0.74 | HTT (0.35) | HTTALDH1A1TSHRFGFR4 | |
| SCHEMBL10556760 | 0.74 | ALOX15 (0.31) | ALDH1A1TSHR | |
| SCHEMBL1199933 | 0.72 | — | — | |
| SCHEMBL29021085 | 0.69 | TDP1 (0.34) | HTTTSHR | |
| SCHEMBL28694555 | 0.69 | HTT (0.33) | HTT | |
| SCHEMBL28446616 | 0.68 | THRB (0.38) | ALDH1A1TSHR | |
| SCHEMBL8850951 | 0.68 | HTT (0.32) | HTT | |
| SCHEMBL3270630 | 0.68 | HTT (0.32) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4556651-A | Secalonic acid derivatives as antitumor agents | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1985-12-03 | — | — | US | disclosed |
| US-4418061-A | ANTITUMOR AGENTS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1983-11-29 | — | — | US | disclosed |