Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylamine SCHEMBL5574544 | 0.81 | ALOX15 (0.42) | KDM4EGAAMAOAMAOBLMNA | |
| Ethylenediamine SCHEMBL5093336 | 0.81 | ALOX15 (0.36) | KDM4EGAAMAOAMAOBLMNA | |
| Ethylene SCHEMBL28215909 | 0.81 | DGAT1 (0.44) | ALDH1A1MAOAMAOBLMNAHSD17B10 | |
| SCHEMBL28902273 | 0.81 | DGAT1 (0.42) | ALDH1A1MAOAMAOBLMNAHSD17B10 | |
| SCHEMBL28325001 | 0.81 | DGAT1 (0.42) | ALDH1A1MAOAMAOBLMNAHSD17B10 | |
| SCHEMBL30234788 | 0.81 | DGAT1 (0.42) | ALDH1A1MAOAMAOBLMNAHSD17B10 | |
| SCHEMBL3094 | 0.81 | — | — | |
| Acrylic Acid SCHEMBL28456927 | 0.80 | LMNA (0.46) | ALDH1A1LMNAHSD17B10DGAT1ALOX15 | |
| Propane SCHEMBL27464056 | 0.79 | ALOX15 (0.43) | GAAMAOAMAOBLMNAHSD17B10 | |
| Methylamine SCHEMBL25305181 | 0.78 | DGAT1 (0.40) | ALDH1A1MAOAMAOBLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7470703-B1 | Yohimbine derivatives and use thereof | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2008-12-30 | — | — | US | disclosed |