SCHEMBL2902218

SCHEMBL2902218

C=CCc1cc(C=O)c(O)c(OC)c1

nearest known ligand 0.73

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.64
MAPT P10636 1/20 0.64
TNKS O95271 1/20 0.60
TNKS2 Q9H2K2 1/20 0.60
ERN1 O75460 11/20 0.57
ALDH1A1 P00352 2/20 0.54
PTGS1 P23219 2/20 0.54
CYP3A4 P08684 1/20 0.54
ALOX5 P09917 1/20 0.54
AR P10275 1/20 0.54
TRPM8 Q7Z2W7 1/20 0.54
PPARG P37231 1/20 0.50
PPARD Q03181 1/20 0.50
PPARA Q07869 1/20 0.50
CCR3 P51677 1/20 0.50
ESR1 P03372 1/20 0.49
ESR2 Q92731 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29539663 1.00 LMNA (0.64) LMNAMAPTTNKSTNKS2ERN1
SCHEMBL20148336 0.91 TNKS2 (0.70) LMNAMAPTTNKSTNKS2ERN1
SCHEMBL14262144 0.89 LMNA (0.69) LMNAMAPTERN1
SCHEMBL22993856 0.87 LMNA (0.68) LMNAMAPTERN1
Methoxyeugenol SCHEMBL293977 0.85 TNKS (0.73) LMNAMAPTTNKSTNKS2ALDH1A1
SCHEMBL212688 0.83 LMNA (0.71) LMNAMAPTERN1
SCHEMBL30785406 0.83 TNKS (0.58) LMNAMAPTTNKSTNKS2ALDH1A1
SCHEMBL9279390 0.83 ERN1 (0.48) LMNAMAPTTNKSTNKS2ERN1
SCHEMBL31130497 0.83 ALDH1A1 (0.51) LMNAMAPTTNKSTNKS2ERN1
SCHEMBL28721890 0.83 ALDH1A1 (0.51) LMNAMAPTTNKSTNKS2ERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111826014-B Non-stick pan with modified tetrafluoroethylene coating and preparation method thereof 浙江乐酷厨具有限公司 2021-09-03 CN claimed
CN-111826014-A Non-stick pan with modified tetrafluoroethylene coating and preparation method thereof 浙江乐酷厨具有限公司 2020-10-27 CN claimed
EP-4665712-A1 COMPOUNDS, THEIR COMPOSITION AND THEIR USE AS NEMATICIDES Bhukhanwala, Komal (IN) 2025-12-24 EP disclosed
WO-2025043316-A1 PROCESS FOR OBTAINING ANTI-INFLAMMATORY COMPOUNDS, SAID COMPOUNDS, PHARMACEUTICAL COMPOSITION AND USE OF SAID COMPOUNDS AND OF THE PHARMACEUTICAL COMPOSITION UNIVERSIDADE ESTADUAL DE CAMPINAS (BR) 2025-03-06 WO disclosed
WO-2024171229-A1 COMPOUNDS, THEIR COMPOSITION AND THEIR USE AS NEMATICIDES BHUKHANWALA KOMAL (IN) 2024-08-22 WO disclosed
CN-116041768-B PH-responsive ultra-smooth antibacterial silicone rubber and preparation method thereof 泰州度博迈医疗器械有限公司 2024-06-25 CN disclosed
CN-118164872-A Eugenol compound containing Schiff base core skeleton, and preparation method and application thereof 贵州大学 2024-06-11 CN disclosed
CN-116041768-A PH-responsive ultra-smooth antibacterial silicone rubber and preparation method thereof 泰州度博迈医疗器械有限公司 2023-05-02 CN disclosed
WO-2022063351-A1 AZULENE HYDRAZIDE-HYDRAZONES AND THEIR USE IN THE TREATMENT OF ONCOLOGIC DISEASES UNIVERZITA KARLOVA (CZ) 2022-03-31 WO disclosed
CN-111826014-B Non-stick pan with modified tetrafluoroethylene coating and preparation method thereof 浙江乐酷厨具有限公司 2021-09-03 CN disclosed
EP-3548501-B1 NOVEL RUTHENIUM COMPLEX, METHOD OF ITS PRODUCTION AND ITS USE IN REACTION OF OLEFINE METATHESIS UNIV WARSZAWSKI (PL) 2021-02-17 EP disclosed
US-7652013-B2 Inhibitors of stearoyl-CoA desaturase HOFFMAN-LA ROCHE INC. (US) 2010-01-26 US disclosed
US-7652013-B2 Inhibitors of stearoyl-CoA desaturase HOFFMAN-LA ROCHE INC. (US) 2010-01-26 US disclosed
US-7652013-B2 Inhibitors of stearoyl-CoA desaturase HOFFMAN-LA ROCHE INC. (US) 2010-01-26 US disclosed
WO-2009074487-A1 INHIBITORS OF STEAROYL-COA DESATURASE F. HOFFMANN-LA ROCHE AG (CH) 2009-06-18 WO disclosed
WO-2009074487-A1 INHIBITORS OF STEAROYL-COA DESATURASE F. HOFFMANN-LA ROCHE AG (CH) 2009-06-18 WO disclosed
US-20090149466-A1 INHIBITORS OF STEAROYL-COA DESATURASE GILLESPIE PAUL 2009-06-11 US disclosed
US-20090149466-A1 INHIBITORS OF STEAROYL-COA DESATURASE GILLESPIE PAUL 2009-06-11 US disclosed
US-20090149466-A1 INHIBITORS OF STEAROYL-COA DESATURASE GILLESPIE PAUL 2009-06-11 US disclosed
US-3978208-A ACETOHYDROXAMIC ACID EISAI CO., LTD. (JA) 1976-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090149466-A1 INHIBITORS OF STEAROYL-COA DESATURASE SCD, SCD5, FADS2 LMNA 2327/4885MAPT 3663/4885TNKS 2934/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.