Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.67 |
| ▸ | HTR7 | P34969 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29022599 | 0.92 | HTR1A (0.74) | HTR1AHTR7MEN1KMT2A | |
| SCHEMBL24069083 | 0.92 | HTR1A (0.57) | HTR1AHTR7KMT2AKDM4ELMNA | |
| SCHEMBL29022589 | 0.85 | HTR1A (0.64) | HTR1AHTR7KMT2A | |
| SCHEMBL25758490 | 0.84 | HTR7 (0.72) | HTR7MEN1KMT2AKDM4ELMNA | |
| SCHEMBL1382312 | 0.80 | HTR1A (1.00) | HTR1AHTR7MEN1KMT2A | |
| SCHEMBL25758479 | 0.80 | KDM1A (0.58) | HTR7KDM4ELMNAGAAMAPT | |
| SCHEMBL1383722 | 0.79 | HTR1A (0.82) | HTR1AHTR7MEN1KMT2A | |
| SCHEMBL25758458 | 0.78 | SLC6A2 (0.61) | MEN1KMT2AKDM4ELMNAGAA | |
| SCHEMBL17374138 | 0.77 | HTR7 (0.66) | HTR1AHTR7KDM4ELMNASMN1; SMN2 | |
| SCHEMBL6568486 | 0.77 | SIGMAR1 (0.72) | HTR7KDM4ELMNAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157124-A | Sulfonamide derivative and pharmaceutical composition for preventing or treating mental diseases containing the same as active ingredient | 大邱庆北尖端医疗产业振兴财团 | 2023-05-23 | — | — | CN | claimed |
| CN-116157124-A | Sulfonamide derivative and pharmaceutical composition for preventing or treating mental diseases containing the same as active ingredient | 大邱庆北尖端医疗产业振兴财团 | 2023-05-23 | — | — | CN | disclosed |
| EP-4159718-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS | Daegu-Gyeongbuk Medical Innovation Foundation (KR) | 2023-04-05 | — | — | EP | disclosed |