Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL558683 | 0.72 | ALDH1A1 (0.42) | ALDH1A1HTT | |
| SCHEMBL2308600 | 0.69 | ALDH1A1 (0.39) | ALDH1A1HTT | |
| SCHEMBL19583420 | 0.62 | CA12 (0.32) | ALDH1A1HTT | |
| SCHEMBL6780333 | 0.60 | ALDH1A1 (0.33) | ALDH1A1HTT | |
| SCHEMBL5336393 | 0.60 | TSHR (0.35) | ALDH1A1HTT | |
| Acetic Acid SCHEMBL4526905 | 0.59 | CA12 (0.34) | ALDH1A1HTT | |
| SCHEMBL11906500 | 0.57 | ALDH1A1 (0.33) | ALDH1A1HTT | |
| SCHEMBL27941 | 0.55 | — | — | |
| SCHEMBL9020270 | 0.55 | — | — | |
| SCHEMBL19972424 | 0.54 | KDM4E (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2212305-A1 | BETA-LACTONE COMPOUNDS | Burnham Institute for Medical Research (US) | 2010-08-04 | — | — | EP | disclosed |
| WO-2009059046-A1 | BETA-LACTONE COMPOUNDS | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2009-05-07 | — | — | WO | disclosed |