Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28533700 | 0.75 | CA12 (0.35) | ALDH1A1HTT | |
| SCHEMBL19583420 | 0.74 | CA12 (0.32) | ALDH1A1HTT | |
| SCHEMBL558683 | 0.71 | ALDH1A1 (0.42) | ALDH1A1HTT | |
| SCHEMBL28518185 | 0.70 | MEN1 (0.31) | ALDH1A1MEN1LMNAMAPTKMT2A | |
| SCHEMBL1524563 | 0.69 | MEN1 (0.31) | ALDH1A1HTTMEN1LMNAKMT2A | |
| SCHEMBL9821807 | 0.68 | HIF1A (0.37) | ALDH1A1MEN1LMNAMAPTKMT2A | |
| SCHEMBL2308600 | 0.67 | ALDH1A1 (0.39) | ALDH1A1HTTLMNAMAPT | |
| Cyclopentane SCHEMBL28946144 | 0.64 | GSK3A (0.35) | ALDH1A1MAPT | |
| Acetic Acid SCHEMBL4526905 | 0.62 | CA12 (0.34) | ALDH1A1HTTLMNAMAPTKMT2A | |
| SCHEMBL2902268 | 0.60 | ALDH1A1 (0.34) | ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696475-B2 | N-PHENYL-N'-(2-CARBOXYPHENYL) UREA, FOR EXAMPLE; CHLORIDE CHANNEL BLOCKERS; SUCH AS FOR TREATING BONE METABOLIC DISORDERS | NEUROSEARCH A/S (DK) | 2004-02-24 | — | — | US | claimed |