SCHEMBL29023286

SCHEMBL29023286

Cn1cnc(S(=O)(=O)N2CC(C(=O)O)C2)c1.[LiH]

nearest known ligand 0.51

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC6A9 P48067 4/20 0.51
TP53 P04637 3/20 0.51
POLB P06746 2/20 0.51
LMNA P02545 3/20 0.49
PKM P14618 1/20 0.49
PAX8 Q06710 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24193812 0.99 SLC6A9 (0.52) SLC6A9TP53POLBLMNAPKM
Lithium SCHEMBL30471840 0.97 SLC6A9 (0.51) SLC6A9TP53POLBLMNAPKM
SCHEMBL4521880 0.84 POLB (0.65) TP53POLBLMNAPKM
Lithium Ion SCHEMBL25352383 0.84 TP53 (0.50) SLC6A9TP53POLBLMNAPKM
SCHEMBL24194778 0.83 TP53 (0.52) SLC6A9TP53POLBLMNA
SCHEMBL29023303 0.79 THRB (0.45) TP53LMNA
SCHEMBL25989047 0.77 THRB (0.46) TP53LMNA
Lithium SCHEMBL30471883 0.76 THRB (0.45) TP53LMNA
SCHEMBL2860180 0.75 SLC6A9 (0.49) SLC6A9TP53POLBLMNAPKM
SCHEMBL16032124 0.75 SLC6A9 (0.48) SLC6A9TP53POLBLMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116323606-A Azetidine derivatives for the treatment of integrin-associated diseases 诺丁汉大学 2023-06-23 CN disclosed