Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24193812 | 0.86 | SLC6A9 (0.52) | POLBTP53LMNAPKM | |
| SCHEMBL2857067 | 0.85 | POLB (0.67) | POLBTP53LMNAMAPTPKM | |
| Lithium SCHEMBL30471840 | 0.84 | SLC6A9 (0.51) | POLBTP53LMNAPKM | |
| SCHEMBL29023286 | 0.84 | SLC6A9 (0.51) | POLBTP53LMNAPKM | |
| SCHEMBL24477715 | 0.82 | LMNA (0.55) | POLBTP53LMNAMAPTPKM | |
| SCHEMBL2860514 | 0.80 | POLB (0.60) | POLBTP53LMNAMAPTPKM | |
| SCHEMBL7137676 | 0.79 | POLB (0.54) | POLBTP53LMNAMAPTPKM | |
| SCHEMBL4534524 | 0.79 | POLB (0.59) | POLBTP53LMNAMAPT | |
| SCHEMBL4534530 | 0.78 | EPHX2 (0.59) | POLBTP53LMNAMAPT | |
| SCHEMBL21670323 | 0.77 | LMNA (0.56) | POLBTP53LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090306048-A1 | PHARMACEUTICAL USE OF SUBSTITUTED PIPERIDINE CARBOXAMIDES | HIGH POINT PHARMACEUTICALS, LLC | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306048-A1 | PHARMACEUTICAL USE OF SUBSTITUTED PIPERIDINE CARBOXAMIDES | HSD11B1, HSD3B1, CES1 | POLB 1203/4885TP53 4809/4885LMNA 3211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.