SCHEMBL29023398

SCHEMBL29023398

CC(C)c1ccc(-c2c(C(C)C)c(O)cc(Cl)c2C(C)C)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.42
CNR2 P34972 1/20 0.42
TYR P14679 3/20 0.40
TRPA1 O75762 1/20 0.40
PTGS1 P23219 1/20 0.40
CACNA1C Q13936 1/20 0.40
PBK Q96KB5 7/20 0.39
ALDH1A1 P00352 2/20 0.39
ALOX12 P18054 2/20 0.39
HTT P42858 2/20 0.39
GAA P10253 1/20 0.39
HIF1A Q16665 1/20 0.39
RNASEH1 O60930 1/20 0.37
KDM4E B2RXH2 1/20 0.37
MDM4 O15151 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9742928 0.75 TYR (0.47) CNR1CNR2TYRTRPA1PTGS1
SCHEMBL10767233 0.73 CNR1 (0.50) CNR1CNR2TYRTRPA1PTGS1
SCHEMBL24838149 0.72 GABRA1 (0.48) CNR1CNR2TYRTRPA1PTGS1
SCHEMBL13748754 0.70 TSHR (0.52) CNR1CNR2ALDH1A1ALOX12HTT
SCHEMBL17707900 0.70 TYR (0.50) CNR1CNR2TYRTRPA1PTGS1
SCHEMBL1493888 0.69 PTGS1 (0.59) CNR1CNR2TYRTRPA1PTGS1
SCHEMBL24636780 0.69 HSD17B10 (0.52) PTGS1ALDH1A1ALOX12HTTHIF1A
SCHEMBL105261 0.69 ALDH1A1 (0.57) CNR1CNR2TYRTRPA1PTGS1
SCHEMBL23079373 0.69 GABRA1 (0.41) ALDH1A1ALOX12HIF1ACA1CA2
SCHEMBL14670464 0.69 GRIA1 (0.39) TYRALDH1A1KDM4ETP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116178449-A Organic electroluminescent material and device 环球展览公司 2023-05-30 CN disclosed
CN-109111487-B Organic electroluminescent material and device 环球展览公司 2023-04-11 CN disclosed