SCHEMBL29023802

SCHEMBL29023802

OB(O)c1c2ccccc2cc2c(B(O)O)c3ccccc3cc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
HSD17B10 Q99714 4/20 0.48
HIF1A Q16665 1/20 0.48
CYP1B1 Q16678 1/20 0.48
TRPM4 Q8TD43 1/20 0.43
NQO2 P16083 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
KDM4E B2RXH2 4/20 0.40
CYP1A2 P05177 3/20 0.40
MEN1 O00255 2/20 0.40
HPGD P15428 2/20 0.40
KMT2A Q03164 2/20 0.40
GLA P06280 1/20 0.40
CYP2C19 P33261 1/20 0.40
TDP1 Q9NUW8 2/20 0.38
MGLL Q99685 2/20 0.38
CYP2A6 P11509 2/20 0.38
TSHR P16473 1/20 0.38
CASP6 P55212 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29414927 0.93 HSD17B10 (0.46) ALDH1A1HSD17B10HIF1ACYP1B1TRPM4
SCHEMBL24958 0.93 HSD17B10 (0.46) ALDH1A1HSD17B10HIF1ACYP1B1TRPM4
Benzene SCHEMBL5134896 0.91 ALDH1A1 (0.50) ALDH1A1HSD17B10HIF1ACYP1B1TRPM4
SCHEMBL29690415 0.86 ALDH1A1 (0.56) ALDH1A1HSD17B10HIF1ACYP1B1TRPM4
SCHEMBL2789059 0.86 ALDH1A1 (0.56) ALDH1A1HSD17B10HIF1ACYP1B1TRPM4
Magnesium Chloride Anhydrous SCHEMBL20694975 0.85 L3MBTL1 (0.42) ALDH1A1HSD17B10HIF1ACYP1B1TRPM4
SCHEMBL31338574 0.83 TRPM4 (0.42) ALDH1A1HSD17B10HIF1ACYP1B1TRPM4
SCHEMBL18253941 0.83 TRPM4 (0.42) ALDH1A1HSD17B10HIF1ACYP1B1TRPM4
SCHEMBL2859827 0.80 TRPM4 (0.36) ALDH1A1HSD17B10HIF1ACYP1B1TRPM4
SCHEMBL702357 0.79 ENPP2 (0.45) ALDH1A1HSD17B10CA1CA2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116283478-A Organic compound and application thereof 阜阳欣奕华材料科技有限公司 2023-06-23 CN disclosed