Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | MMP12 | P39900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15225080 | 0.78 | DAO (0.37) | — | |
| SCHEMBL2353580 | 0.77 | DAO (0.31) | — | |
| SCHEMBL290331 | 0.76 | MGLL (0.45) | HDAC6HSD17B1HSD17B2MGLL | |
| SCHEMBL15225532 | 0.75 | MGLL (0.47) | MGLL | |
| SCHEMBL14830420 | 0.75 | MGLL (0.51) | MGLL | |
| SCHEMBL577885 | 0.72 | — | — | |
| SCHEMBL486247 | 0.72 | SMN1; SMN2 (0.30) | — | |
| SCHEMBL119711 | 0.71 | TRPV6 (0.39) | MGLL | |
| SCHEMBL18833188 | 0.71 | CA1 (0.34) | MGLL | |
| SCHEMBL584051 | 0.70 | ALDH1A1 (0.33) | HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |