Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.40 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 7/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24133538 | 1.00 | BRD4 (0.40) | BRD4MAP3K12KMOHRH4POLB | |
| SCHEMBL29858105 | 0.82 | MET (0.52) | BRD4MAP3K12KMO | |
| SCHEMBL29858142 | 0.82 | MET (0.52) | BRD4MAP3K12KMO | |
| SCHEMBL26917087 | 0.82 | MET (0.52) | BRD4MAP3K12KMO | |
| SCHEMBL26916644 | 0.82 | MET (0.52) | BRD4MAP3K12KMO | |
| SCHEMBL16212180 | 0.82 | MET (0.52) | BRD4MAP3K12KMO | |
| SCHEMBL31757210 | 0.78 | ALDH1A1 (0.42) | BRD4KMOLMNAADRA2B | |
| SCHEMBL29024329 | 0.78 | ALDH1A1 (0.42) | BRD4KMOLMNAADRA2B | |
| SCHEMBL25889481 | 0.78 | ALDH1A1 (0.42) | BRD4KMOLMNAADRA2B | |
| SCHEMBL24133532 | 0.76 | LPL (0.37) | BRD4MAP3K12KMOFFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115956070-A | Sulfonamide compounds | 阿纳克西斯制药股份有限公司 | 2023-04-11 | — | — | CN | disclosed |