Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.38 |
| ▸ | LPAR6 | P43657 | 2/20 | 0.38 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8950367 | 1.00 | USP2 (0.46) | USP2DNM1ALDH1A1CNR1CNR2 | |
| SCHEMBL28164046 | 0.98 | CNR1 (0.44) | USP2DNM1ALDH1A1CNR1CNR2 | |
| SCHEMBL16829859 | 0.94 | USP2 (0.50) | USP2DNM1ALDH1A1CNR1CNR2 | |
| SCHEMBL29372863 | 0.94 | USP2 (0.50) | USP2DNM1ALDH1A1CNR1CNR2 | |
| SCHEMBL831869 | 0.91 | TSHR (0.39) | USP2DNM1ALDH1A1CNR1CNR2 | |
| SCHEMBL5591161 | 0.86 | HTT (0.52) | USP2ALDH1A1CNR1CNR2MEN1 | |
| SCHEMBL744018 | 0.86 | USP2 (0.40) | USP2DNM1ALDH1A1CNR1CNR2 | |
| SCHEMBL27835501 | 0.83 | DNM1 (0.47) | DNM1THRBLPAR1LPAR3LPAR2 | |
| SCHEMBL5013566 | 0.82 | THRB (0.35) | USP2ALDH1A1THRBLMNAHSD17B10 | |
| SCHEMBL10004744 | 0.80 | DNM1 (0.43) | DNM1ALDH1A1CNR1CNR2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110655546-B | Sofosbuvir derivative, and preparation method and application thereof | 安徽贝克制药股份有限公司 | 2023-05-16 | — | — | CN | disclosed |