Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8950367 | 0.86 | USP2 (0.46) | USP2ALDH1A1HTTMEN1THRB | |
| SCHEMBL29024409 | 0.86 | USP2 (0.46) | USP2ALDH1A1HTTMEN1THRB | |
| SCHEMBL7097326 | 0.85 | ALDH1A1 (0.44) | ALDH1A1THRBTSHR | |
| SCHEMBL28164046 | 0.83 | CNR1 (0.44) | USP2ALDH1A1HTTMEN1THRB | |
| SCHEMBL831869 | 0.81 | TSHR (0.39) | USP2ALDH1A1HTTMEN1THRB | |
| SCHEMBL5591161 | 0.81 | HTT (0.52) | USP2ALDH1A1HTTMEN1THRB | |
| SCHEMBL28642630 | 0.80 | MEN1 (0.32) | ALDH1A1HTTMEN1THRBKMT2A | |
| SCHEMBL2726362 | 0.80 | DNM1 (0.31) | ALDH1A1LPAR1LPAR3LPAR2DNM1 | |
| SCHEMBL16829859 | 0.79 | USP2 (0.50) | USP2ALDH1A1HTTMEN1THRB | |
| SCHEMBL363639 | 0.79 | ALDH1A1 (0.46) | ALDH1A1HTTMEN1THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2429986-A1 | HALOALKYL HETEROARYL BENZAMIDE COMPOUNDS | Romark Laboratories, L.C. (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010132404-A1 | HALOALKYL HETEROARYL BENZAMIDE COMPOUNDS | ROMARK LABORATORIES L.C. (US) | 2010-11-18 | — | — | WO | disclosed |