Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28906669 | 0.97 | LMNA (0.61) | LMNAL3MBTL1EPHX2TDP1SPHK1 | |
| SCHEMBL18661335 | 0.95 | LMNA (0.67) | LMNAL3MBTL1EPHX2TDP1SPHK1 | |
| SCHEMBL28430036 | 0.92 | LMNA (0.63) | LMNAL3MBTL1EPHX2TDP1SPHK1 | |
| SCHEMBL28606330 | 0.89 | LMNA (0.63) | LMNAL3MBTL1EPHX2TDP1SPHK1 | |
| SCHEMBL26907107 | 0.88 | LMNA (0.66) | LMNAL3MBTL1TDP1NAAATSHR | |
| SCHEMBL6382531 | 0.85 | EPHX2 (0.56) | LMNAL3MBTL1EPHX2TDP1SPHK1 | |
| SCHEMBL20023124 | 0.83 | ALDH1A1 (0.49) | LMNAL3MBTL1EPHX2TDP1NAAA | |
| SCHEMBL9871595 | 0.83 | ALDH1A1 (0.62) | LMNAL3MBTL1EPHX2TDP1NAAA | |
| SCHEMBL1838924 | 0.83 | LMNA (0.86) | LMNATDP1NAAASMN1; SMN2 | |
| SCHEMBL1833113 | 0.83 | LMNA (0.86) | LMNATDP1NAAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116368146-A | Novel ligands for asialoglycoprotein receptors | 赛诺菲 | 2023-06-30 | — | — | CN | disclosed |