Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28934013 | 0.95 | ALDH1A1 (0.65) | ALDH1A1EPHX2L3MBTL1TDP1NAAA | |
| SCHEMBL343443 | 0.88 | ALDH1A1 (0.69) | ALDH1A1L3MBTL1TDP1NAAATSHR | |
| SCHEMBL342830 | 0.86 | ALDH1A1 (0.67) | ALDH1A1EPHX2L3MBTL1TDP1NAAA | |
| SCHEMBL9870809 | 0.83 | EPHX2 (0.58) | ALDH1A1EPHX2L3MBTL1TDP1TSHR | |
| SCHEMBL8984483 | 0.83 | EPHX2 (0.58) | ALDH1A1EPHX2L3MBTL1TDP1TSHR | |
| SCHEMBL9872209 | 0.83 | EPHX2 (0.58) | ALDH1A1EPHX2L3MBTL1TDP1TSHR | |
| SCHEMBL2638931 | 0.83 | EPHX2 (0.58) | ALDH1A1EPHX2L3MBTL1TDP1TSHR | |
| SCHEMBL20023124 | 0.83 | ALDH1A1 (0.49) | ALDH1A1EPHX2L3MBTL1TDP1NAAA | |
| SCHEMBL839310 | 0.83 | EPHX2 (0.58) | ALDH1A1EPHX2L3MBTL1TDP1TSHR | |
| SCHEMBL29025355 | 0.83 | LMNA (0.65) | ALDH1A1EPHX2L3MBTL1TDP1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5070139-A | PLATELET ACTIVATING FACTOR ANTAGONISTS, HYPOTENSIVES | J. URIACH & CIA. S.A. (ES) | 1991-12-03 | — | — | US | disclosed |
| US-4940706-A | 2,4-disubstituted 1,3-dioxolanes and pharmaceutical use | J. URIACH & CIA, S.A. (ES) | 1990-07-10 | — | — | US | disclosed |
| EP-0312041-A2 | 2,4-Disubstituted 1,3-dioxolanes | J. URIACH & CIA. S.A. (ES) | 1989-04-19 | — | — | EP | disclosed |