Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29025526 | 1.00 | LMNA (0.44) | LMNAKDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL29025672 | 0.88 | MAP4K4 (0.47) | LMNAKDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL29025669 | 0.88 | MAP4K4 (0.47) | LMNAKDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL29025640 | 0.80 | LMNA (0.34) | LMNAALDH1A1CYP1A2FAAH | |
| SCHEMBL26667486 | 0.80 | HDAC1 (0.46) | LMNAKDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL26667483 | 0.80 | HDAC1 (0.46) | LMNAKDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL24302494 | 0.75 | MEN1 (0.45) | KDM4EALDH1A1GAAHDAC1HDAC6 | |
| SCHEMBL29025543 | 0.74 | ALDH1A1 (0.44) | LMNAKDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL29025546 | 0.74 | ALDH1A1 (0.44) | LMNAKDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL10324369 | 0.73 | LMNA (0.56) | LMNACYP1A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116367832-A | Substituted heteroaryl compounds and uses thereof | 苏州华明道康生物医药有限公司 | 2023-06-30 | — | — | CN | disclosed |