Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29025669 | 0.85 | MAP4K4 (0.47) | LMNAALDH1A1MAPTTDP1MAP4K4 | |
| SCHEMBL29025672 | 0.85 | MAP4K4 (0.47) | LMNAALDH1A1MAPTTDP1MAP4K4 | |
| SCHEMBL29025524 | 0.80 | LMNA (0.44) | LMNAALDH1A1FAAHCYP1A2 | |
| SCHEMBL29025526 | 0.80 | LMNA (0.44) | LMNAALDH1A1FAAHCYP1A2 | |
| SCHEMBL29025543 | 0.70 | ALDH1A1 (0.44) | LMNAALDH1A1MAPTTDP1FAAH | |
| SCHEMBL29025546 | 0.70 | ALDH1A1 (0.44) | LMNAALDH1A1MAPTTDP1FAAH | |
| SCHEMBL10324369 | 0.66 | LMNA (0.56) | LMNATDP1CYP1A2 | |
| SCHEMBL31121750 | 0.65 | HDAC6 (0.40) | LMNA | |
| SCHEMBL10324410 | 0.62 | LMNA (0.54) | LMNATDP1CYP1A2 | |
| SCHEMBL14876888 | 0.61 | CHRNB2 (0.45) | LMNAALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116367832-A | Substituted heteroaryl compounds and uses thereof | 苏州华明道康生物医药有限公司 | 2023-06-30 | — | — | CN | disclosed |