Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29025560 | 0.86 | USP2 (0.43) | LMNAUSP2POLBKDM4ERAB9A | |
| SCHEMBL30504316 | 0.86 | USP2 (0.43) | LMNAUSP2POLBKDM4ERAB9A | |
| SCHEMBL29025559 | 0.86 | USP2 (0.43) | LMNAUSP2POLBKDM4ERAB9A | |
| SCHEMBL30504318 | 0.83 | LMNA (0.41) | LMNAUSP2KDM4EALDH1A1MAPT | |
| SCHEMBL29025574 | 0.83 | LMNA (0.41) | LMNAUSP2KDM4EALDH1A1MAPT | |
| SCHEMBL24302524 | 0.83 | LMNA (0.41) | LMNAUSP2KDM4EALDH1A1MAPT | |
| SCHEMBL26667409 | 0.79 | USP2 (0.43) | LMNAUSP2POLBKDM4ERAB9A | |
| SCHEMBL26667416 | 0.79 | USP2 (0.43) | LMNAUSP2POLBKDM4ERAB9A | |
| SCHEMBL29025635 | 0.78 | NPC1 (0.40) | LMNAUSP2KDM4ERAB9AALDH1A1 | |
| SCHEMBL29025645 | 0.72 | SMN1; SMN2 (0.39) | LMNAPOLBKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116367832-A | Substituted heteroaryl compounds and uses thereof | 苏州华明道康生物医药有限公司 | 2023-06-30 | — | — | CN | disclosed |