Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30504330 | 0.82 | DRD2 (0.41) | SMN1; SMN2ALDH1A1KMT2APOLBMEN1 | |
| SCHEMBL24302523 | 0.82 | DRD2 (0.41) | SMN1; SMN2ALDH1A1KMT2APOLBMEN1 | |
| SCHEMBL29025648 | 0.82 | DRD2 (0.41) | SMN1; SMN2ALDH1A1KMT2APOLBMEN1 | |
| SCHEMBL26667477 | 0.78 | ALDH1A1 (0.42) | ALDH1A1KMT2APOLBHPGDKDM4E | |
| SCHEMBL26667481 | 0.78 | ALDH1A1 (0.42) | ALDH1A1KMT2APOLBHPGDKDM4E | |
| SCHEMBL29025571 | 0.72 | LMNA (0.41) | SMN1; SMN2ALDH1A1POLBLMNAHPGD | |
| SCHEMBL29025542 | 0.71 | AGTR1 (0.48) | SMN1; SMN2ALDH1A1KMT2APOLBMEN1 | |
| SCHEMBL29025635 | 0.66 | NPC1 (0.40) | SMN1; SMN2ALDH1A1KMT2AMEN1HSP90AA1 | |
| SCHEMBL3484796 | 0.65 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1HTTPOLBHPGD | |
| SCHEMBL15207986 | 0.65 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1KMT2AHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116367832-A | Substituted heteroaryl compounds and uses thereof | 苏州华明道康生物医药有限公司 | 2023-06-30 | — | — | CN | disclosed |