Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29025575 | 0.84 | MAPT (0.42) | NPC1RAB9ASMN1; SMN2TP53HDAC3 | |
| SCHEMBL29025572 | 0.84 | MAPT (0.42) | NPC1RAB9ASMN1; SMN2TP53HDAC3 | |
| SCHEMBL29025517 | 0.82 | RAB9A (0.46) | NPC1RAB9ASMN1; SMN2TP53HDAC3 | |
| SCHEMBL29025638 | 0.81 | UTS2R (0.43) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL29025571 | 0.78 | LMNA (0.41) | NPC1RAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL29025576 | 0.73 | FAAH (0.40) | RAB9ASMN1; SMN2MAPTLMNAALDH1A1 | |
| SCHEMBL27945596 | 0.69 | ALDH1A1 (0.45) | MAPTLMNAALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL1009889 | 0.66 | PPARA (0.48) | PPARG | |
| SCHEMBL29025546 | 0.65 | ALDH1A1 (0.44) | NPC1RAB9ASMN1; SMN2TP53HDAC3 | |
| SCHEMBL29025543 | 0.65 | ALDH1A1 (0.44) | NPC1RAB9ASMN1; SMN2TP53HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116367832-A | Substituted heteroaryl compounds and uses thereof | 苏州华明道康生物医药有限公司 | 2023-06-30 | — | — | CN | disclosed |