Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29025572 | 1.00 | MAPT (0.42) | MAPTTDP1LMNAUSP2ADORA2A | |
| SCHEMBL29025635 | 0.84 | NPC1 (0.40) | MAPTTDP1LMNAUSP2ADORA2A | |
| SCHEMBL29025546 | 0.81 | ALDH1A1 (0.44) | MAPTTDP1LMNAHDAC3HDAC4 | |
| SCHEMBL29025543 | 0.81 | ALDH1A1 (0.44) | MAPTTDP1LMNAHDAC3HDAC4 | |
| SCHEMBL29025638 | 0.77 | UTS2R (0.43) | MAPTTDP1LMNAUSP2ADORA2A | |
| SCHEMBL30504316 | 0.75 | USP2 (0.43) | MAPTLMNAUSP2ALDH1A1HSD17B10 | |
| SCHEMBL29025560 | 0.75 | USP2 (0.43) | MAPTLMNAUSP2ALDH1A1HSD17B10 | |
| SCHEMBL29025559 | 0.75 | USP2 (0.43) | MAPTLMNAUSP2ALDH1A1HSD17B10 | |
| SCHEMBL30504331 | 0.69 | RAB9A (0.40) | LMNAHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL29025539 | 0.69 | RAB9A (0.40) | LMNAHDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116367832-A | Substituted heteroaryl compounds and uses thereof | 苏州华明道康生物医药有限公司 | 2023-06-30 | — | — | CN | disclosed |