SCHEMBL2902567

SCHEMBL2902567

CC(C)(C)C(=O)Nc1c[c]cc(C(F)(F)F)c1

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.47
▸ MAPT P10636 4/20 0.42
▸ ALDH1A1 P00352 3/20 0.41
▸ TP53 P04637 1/20 0.41
▸ LMNA P02545 1/20 0.41
▸ HTT P42858 1/20 0.41
▸ GAA P10253 2/20 0.41
▸ NPSR1 Q6W5P4 1/20 0.41
▸ GPR35 Q9HC97 1/20 0.40
▸ NPY2R P49146 1/20 0.39
▸ KDR P35968 1/20 0.38
▸ CNR2 P34972 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5126806 0.87 MEN1 (0.43) L3MBTL1MAPTTP53LMNAHTT
SCHEMBL2894937 0.83 KIF11 (0.46) L3MBTL1MAPTTP53LMNAGPR35
SCHEMBL23148069 0.81 MAPT (0.62) L3MBTL1MAPTALDH1A1LMNAGAA
SCHEMBL686791 0.80 RXFP1 (0.48) L3MBTL1MAPTTP53LMNAGPR35
SCHEMBL5115340 0.76 KDM4E (0.46) L3MBTL1MAPTALDH1A1LMNAHTT
SCHEMBL30977683 0.75 TP53 (0.65) L3MBTL1MAPTALDH1A1TP53LMNA
SCHEMBL4455493 0.75 TP53 (0.65) L3MBTL1MAPTALDH1A1TP53LMNA
SCHEMBL28197800 0.74 AR (0.56) L3MBTL1MAPTALDH1A1LMNAHTT
SCHEMBL3736169 0.74 L3MBTL1 (0.73) L3MBTL1MAPTALDH1A1LMNAHTT
SCHEMBL5118270 0.73 KIF11 (0.44) L3MBTL1MAPTALDH1A1TP53LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100305124-A1 Acylated Aminopyridine and Aminopyridazine Insecticides BAYER CROPSCIENCE AG (DE) 2010-12-02 — — US disclosed
EP-2236505-A1 Acylated aminopyridines and pyridazines as insecticides Bayer CropScience AG (DE) 2010-10-06 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100305124-A1 Acylated Aminopyridine and Aminopyridazine Insecticides AAAS, DDT, QDPR L3MBTL1 1263/4885MAPT 3480/4885ALDH1A1 551/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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