Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22076882 | 0.76 | GAA (0.36) | GAA | |
| SCHEMBL29025834 | 0.76 | GAA (0.36) | GAA | |
| SCHEMBL30478691 | 0.71 | TBK1 (0.33) | SMN1; SMN2EGLN2RET | |
| SCHEMBL30478686 | 0.71 | TBK1 (0.33) | SMN1; SMN2EGLN2RET | |
| SCHEMBL30125784 | 0.71 | BCHE (0.40) | RAB9ANPC1 | |
| SCHEMBL4014542 | 0.70 | GAA (0.44) | RAB9ANPC1SMN1; SMN2GAA | |
| SCHEMBL4014545 | 0.70 | GAA (0.44) | RAB9ANPC1SMN1; SMN2GAA | |
| SCHEMBL14191690 | 0.70 | GAA (0.44) | RAB9ANPC1SMN1; SMN2GAA | |
| SCHEMBL30126556 | 0.69 | STK17B (0.37) | RAB9ANPC1 | |
| SCHEMBL8116209 | 0.69 | CYP17A1 (0.39) | EGLN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109422755-B | Nitrogen-containing heterocyclic compound, preparation method, intermediate, composition and application | 上海医药集团股份有限公司 | 2023-07-04 | — | — | CN | disclosed |