Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | LATS1 | O95835 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | FPR3 | P25089 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30126556 | 0.94 | STK17B (0.37) | BCHEDDB1CRBNMALT1KDM4E | |
| SCHEMBL28841998 | 0.82 | ALDH1A1 (0.37) | NSD2TRPA1POLBAAK1AR | |
| SCHEMBL28842000 | 0.82 | ALDH1A1 (0.37) | NSD2TRPA1POLBAAK1AR | |
| SCHEMBL30126737 | 0.79 | DDB1 (0.45) | BCHEDDB1CRBNMALT1NSD2 | |
| SCHEMBL23099618 | 0.76 | IMPDH2 (0.46) | BCHEDDB1CRBNAAK1 | |
| SCHEMBL30127307 | 0.75 | RECQL (0.43) | BCHEDDB1CRBNMALT1TRPA1 | |
| SCHEMBL20605289 | 0.73 | ALDH1A1 (0.40) | NPC1RAB9A | |
| SCHEMBL20605293 | 0.73 | ALDH1A1 (0.40) | NPC1RAB9A | |
| SCHEMBL4897023 | 0.73 | BCHE (0.48) | BCHEDDB1CRBNMALT1CA1 | |
| SCHEMBL2249224 | 0.72 | ALDH1A1 (0.37) | KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266458-A1 | 6-HETEROCYCLOALKYL-QUINAZOLINE DERIVATIVES AND USES THEREOF | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |