Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.33 |
| ▸ | HTR1D | P28221 | 2/20 | 0.32 |
| ▸ | HTR1B | P28222 | 2/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | QDPR | P09417 | 2/20 | 0.31 |
| ▸ | EED | O75530 | 1/20 | 0.31 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.31 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.31 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
| ▸ | LIPE | Q05469 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30478691 | 1.00 | TBK1 (0.33) | TBK1NAMPTHTR1DHTR1BNR1H2 | |
| SCHEMBL29025865 | 0.87 | KMT2A (0.35) | NAMPTHTR1DHTR1BQDPRKMT2A | |
| SCHEMBL29025867 | 0.87 | KMT2A (0.35) | NAMPTHTR1DHTR1BQDPRKMT2A | |
| SCHEMBL30478687 | 0.85 | NAMPT (0.45) | TBK1NAMPTNR1H2NR1H3EED | |
| SCHEMBL29025848 | 0.81 | QDPR (0.41) | NAMPTQDPRKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29025852 | 0.81 | QDPR (0.41) | NAMPTQDPRKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7677344 | 0.71 | NAMPT (0.39) | NAMPTHTR1DHTR1BKMT2ALIPE | |
| SCHEMBL29025844 | 0.71 | RAB9A (0.35) | SMN1; SMN2RETEGLN2 | |
| SCHEMBL1368952 | 0.69 | NAMPT (0.36) | NAMPTHTR1DHTR1BGPR119LIPE | |
| SCHEMBL25353312 | 0.69 | ALDH1A1 (0.45) | NAMPTNR1H2NR1H3KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109422755-B | Nitrogen-containing heterocyclic compound, preparation method, intermediate, composition and application | 上海医药集团股份有限公司 | 2023-07-04 | — | — | CN | disclosed |