Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29025990 | 0.82 | KDM4E (0.40) | KDM4EHPGDMEN1KMT2ANPSR1 | |
| SCHEMBL28352445 | 0.78 | KDM4E (0.37) | KDM4EHPGDMEN1KMT2ANPSR1 | |
| SCHEMBL29025968 | 0.78 | TARBP2 (0.50) | KDM4EHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29025979 | 0.78 | LTA4H (0.41) | KDM4EHPGDMEN1KMT2ANPSR1 | |
| SCHEMBL28356105 | 0.77 | HEXA (0.37) | KDM4EHPGDCYP2C9CYP2C19CYP1A2 | |
| SCHEMBL29025969 | 0.74 | KDM4E (0.57) | KDM4EHPGDMEN1KMT2ANPSR1 | |
| SCHEMBL29025988 | 0.73 | HRH2 (0.37) | MAPTALDH1A1CYP17A1 | |
| SCHEMBL834546 | 0.65 | CA1 (0.61) | KDM4EMEN1KMT2ANPSR1NPC1 | |
| SCHEMBL28330426 | 0.64 | RAB9A (0.56) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12203937 | 0.64 | NQO1 (0.67) | KDM4EHPGDNPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770209-B | Novel 5-hydroxypyridine compounds useful as P2X1 and P2X3 receptor antagonists and pharmaceutical compositions containing the same | 光州科学技术院 | 2023-06-30 | — | — | CN | disclosed |