Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARBP2 | Q15633 | 2/20 | 0.50 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.50 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5192166 | 0.79 | TARBP2 (0.75) | TARBP2PDCD4NPC1RAB9AMAPT | |
| SCHEMBL29025982 | 0.78 | KDM4E (0.41) | NPC1RAB9AMAPTPOLBSMN1; SMN2 | |
| SCHEMBL29025990 | 0.76 | KDM4E (0.40) | NPC1RAB9AMAPTPOLBSMN1; SMN2 | |
| SCHEMBL28356202 | 0.76 | TARBP2 (0.51) | TARBP2PDCD4NPC1RAB9AMAPT | |
| SCHEMBL28352445 | 0.73 | KDM4E (0.37) | NPC1RAB9AMAPTPOLBSMN1; SMN2 | |
| SCHEMBL29025979 | 0.73 | LTA4H (0.41) | NPC1RAB9AMAPTGAASMN1; SMN2 | |
| SCHEMBL28356105 | 0.71 | HEXA (0.37) | NPBWR1MAPTPOLBALDH1A1KDM4E | |
| SCHEMBL12426320 | 0.70 | FBP1 (0.44) | TARBP2PDCD4NPC1RAB9AMAPT | |
| SCHEMBL29025969 | 0.69 | KDM4E (0.57) | NPC1RAB9AMAPTPOLBSMN1; SMN2 | |
| SCHEMBL28295529 | 0.68 | TARBP2 (0.73) | TARBP2PDCD4NPBWR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770209-B | Novel 5-hydroxypyridine compounds useful as P2X1 and P2X3 receptor antagonists and pharmaceutical compositions containing the same | 光州科学技术院 | 2023-06-30 | — | — | CN | disclosed |