Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 2/20 | 0.42 |
| ▸ | PDE6D | O43924 | 1/20 | 0.42 |
| ▸ | PDE6A | P16499 | 1/20 | 0.42 |
| ▸ | PDE6G | P18545 | 1/20 | 0.42 |
| ▸ | PDE6B | P35913 | 1/20 | 0.42 |
| ▸ | PDE6C | P51160 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5055900 | 0.85 | KDM4E (0.48) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5778710 | 0.84 | SMN1; SMN2 (0.52) | MAPTKDM4EL3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL16974089 | 0.81 | KDM4E (0.50) | MAPTKDM4EMEN1HSP90AA1CRHBP | |
| SCHEMBL27172669 | 0.79 | HDAC4 (0.56) | HDAC4HDAC6 | |
| SCHEMBL5779014 | 0.78 | PDE3B (0.49) | MAPTKDM4EALOX5RAB9ASMN1; SMN2 | |
| SCHEMBL5777232 | 0.78 | KDM4E (0.49) | KDM4EALDH1A1 | |
| SCHEMBL3356162 | 0.76 | KMT2A (0.49) | MAPTKDM4EMEN1HSP90AA1KMT2A | |
| SCHEMBL24208448 | 0.75 | ALOX5 (0.47) | MAPTKDM4EMEN1HSP90AA1CRHBP | |
| SCHEMBL5820787 | 0.75 | PDE3B (0.42) | MAPTKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL69229 | 0.75 | KDM4E (0.54) | MAPTKDM4EMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157394-A | Compounds and compositions for the treatment of diseases associated with STING activity | 艾福姆德尤股份有限公司 | 2023-05-23 | — | — | CN | disclosed |