Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.40 |
| ▸ | POLQ | O75417 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5779565 | 0.85 | L3MBTL1 (0.48) | KDM4EARTSHRALDH1A1POLB | |
| SCHEMBL5778710 | 0.79 | SMN1; SMN2 (0.52) | KDM4ETSHRALDH1A1POLBHSD17B10 | |
| SCHEMBL29026435 | 0.78 | MAPT (0.49) | KDM4EALDH1A1 | |
| SCHEMBL5055900 | 0.76 | KDM4E (0.48) | KDM4EALDH1A1 | |
| SCHEMBL29025464 | 0.76 | TSHR (0.41) | KDM4ETSHRALDH1A1 | |
| SCHEMBL1994129 | 0.75 | TSHR (0.67) | KDM4ETSHRALDH1A1CACNA1CHSD17B10 | |
| SCHEMBL7512080 | 0.75 | TSHR (0.50) | KDM4ETSHRALDH1A1POLBHSD17B10 | |
| SCHEMBL3356162 | 0.74 | KMT2A (0.49) | KDM4ETSHRALDH1A1HSD17B10MAPK1 | |
| SCHEMBL5779014 | 0.73 | PDE3B (0.49) | KDM4ETSHRPOLBMAPK1 | |
| SCHEMBL69229 | 0.73 | KDM4E (0.54) | KDM4ETSHRALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678181-A2 | A2B ADENOSINE RECEPTOR ANTAGONISTS | CV THERAPEUTICS, INC. (US) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042534-A2 | A2B ADENOSINE RECEPTOR ANTAGONISTS | CV THERAPEUTICS, INC. (US) | 2005-05-12 | — | — | WO | disclosed |