Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxiniacic Acid SCHEMBL129209 | 0.81 | MEN1 (1.00) | KMT2AMEN1GPR84NAPRTL3MBTL1 | |
| Oxiniacic Acid SCHEMBL29766756 | 0.81 | MEN1 (1.00) | KMT2AMEN1GPR84NAPRTL3MBTL1 | |
| 2-Chloropyridine SCHEMBL7769567 | 0.74 | TDP1 (0.76) | KMT2ATDP1NAPRTL3MBTL1LMNA | |
| Isonicotinic Acid SCHEMBL28979028 | 0.73 | NAPRT (0.61) | KMT2AMEN1TDP1KDM4EKDM6B | |
| Niacin SCHEMBL27969761 | 0.73 | ALDH1A1 (0.68) | KMT2ATDP1KDM4EKDM6BKDM4A | |
| 2-Chloropyridine SCHEMBL28051574 | 0.72 | TDP1 (0.73) | KMT2ATDP1NAPRTL3MBTL1LMNA | |
| 2-Chloropyridine SCHEMBL5718309 | 0.72 | TDP1 (0.73) | KMT2ATDP1NAPRTL3MBTL1LMNA | |
| SCHEMBL10899428 | 0.71 | MEN1 (0.71) | KMT2AMEN1TDP1GPR84L3MBTL1 | |
| SCHEMBL10920085 | 0.71 | MEN1 (0.71) | KMT2AMEN1GPR84L3MBTL1ABL1 | |
| 2-Chloropyridine SCHEMBL28051573 | 0.70 | TDP1 (0.70) | KMT2ATDP1KDM4ENAPRTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114539135-B | Novel salt form of levamlodipine as well as preparation method and application thereof | 复旦大学 | 2023-07-04 | — | — | CN | disclosed |