SCHEMBL29026563

SCHEMBL29026563

O=[C][C@@H]1CCCN1c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.49
HRH3 Q9Y5N1 3/20 0.44
DPP4 P27487 1/20 0.44
DPP8 Q6V1X1 1/20 0.44
DPP9 Q86TI2 1/20 0.44
DPP7 Q9UHL4 1/20 0.44
SIRT6 Q8N6T7 2/20 0.43
ALDH1A1 P00352 2/20 0.43
POLB P06746 1/20 0.43
ADRB1 P08588 1/20 0.43
LMNA P02545 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6493247 0.82 MAPT (0.56) MAPTHRH3SIRT6ALDH1A1POLB
SCHEMBL8448356 0.78 HRH3 (0.56) MAPTHRH3SIRT6ALDH1A1POLB
SCHEMBL6719932 0.78 HRH3 (0.56) MAPTHRH3SIRT6ALDH1A1POLB
SCHEMBL3767119 0.77 KMT2A (0.44) MAPTALDH1A1MEN1KMT2A
SCHEMBL3767117 0.77 KMT2A (0.44) MAPTALDH1A1MEN1KMT2A
SCHEMBL28682959 0.76 MAPT (0.49) MAPTHRH3SIRT6ALDH1A1POLB
SCHEMBL15828757 0.75 MAPT (0.49) MAPTHRH3SIRT6ALDH1A1POLB
SCHEMBL12006408 0.75 MAPT (0.47) MAPTHRH3SIRT6ALDH1A1POLB
SCHEMBL6095682 0.75 MAPT (0.47) MAPTHRH3SIRT6ALDH1A1POLB
SCHEMBL3552399 0.75 MAPT (0.56) MAPTALDH1A1POLBKMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116349425-A OFET with a multilayer organic semiconductor having a high on/off ratio 元平台技术有限公司 2023-06-27 CN claimed
CN-116326239-A Field effect transistor with high carrier mobility and in-situ insulated organic semiconductor layer 元平台技术有限公司 2023-06-23 CN claimed
CN-116349425-A OFET with a multilayer organic semiconductor having a high on/off ratio 元平台技术有限公司 2023-06-27 CN disclosed