Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6719932 | 0.85 | HRH3 (0.56) | MAPTSIRT6ALDH1A1POLBADRB1 | |
| SCHEMBL8448356 | 0.85 | HRH3 (0.56) | MAPTSIRT6ALDH1A1POLBADRB1 | |
| SCHEMBL2884332 | 0.82 | SIRT6 (0.50) | MAPTSIRT6ALDH1A1POLBADRB1 | |
| SCHEMBL29026563 | 0.82 | MAPT (0.49) | MAPTSIRT6ALDH1A1POLBADRB1 | |
| SCHEMBL28682959 | 0.82 | MAPT (0.49) | MAPTSIRT6ALDH1A1POLBADRB1 | |
| SCHEMBL3552399 | 0.81 | MAPT (0.56) | MAPTALDH1A1POLBKMT2AMAPK1 | |
| SCHEMBL15828757 | 0.81 | MAPT (0.49) | MAPTSIRT6ALDH1A1POLBADRB1 | |
| SCHEMBL12006408 | 0.81 | MAPT (0.47) | MAPTSIRT6ALDH1A1POLBADRB1 | |
| SCHEMBL3552397 | 0.81 | MAPT (0.56) | MAPTALDH1A1POLBKMT2AMAPK1 | |
| SCHEMBL223024 | 0.81 | MAPT (0.47) | MAPTSIRT6ALDH1A1POLBADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6923835-B2 | Bis-para-phenylenediamine derivatives comprising a pyrrolidyl group and use of these derivatives for dyeing keratin fibres | L'OREAL S.A. (FR) | 2005-08-02 | — | — | US | disclosed |
| US-20040123401-A1 | Bis-para-phenylenediamine derivatives comprising a pyrrolidyl group and use of these derivatives for dyeing keratin fibres | L'OREAL S.A. (FR) | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040123401-A1 | Bis-para-phenylenediamine derivatives comprising a pyrrolidyl group and use of these derivatives for dyeing keratin fibres | KRT18, VIM, CDC73 | MAPT 808/4885SIRT6 3846/4885ALDH1A1 1741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.