Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.34 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24100049 | 0.86 | MAPT (0.49) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL29364096 | 0.78 | MAPT (0.46) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL16053849 | 0.78 | MAPT (0.46) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL16084787 | 0.78 | MAPT (0.46) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9706260 | 0.76 | MAPT (0.55) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL9706065 | 0.74 | MAPT (0.69) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL24170556 | 0.73 | POLB (0.41) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL17476226 | 0.72 | HRH4 (0.40) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9706088 | 0.72 | MAPK1 (0.50) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL24176382 | 0.72 | POLB (0.43) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323614-A | Thioate derivatives of RABEXIMOD for the treatment of inflammatory and autoimmune disorders | 维洛诺瓦医药公司 | 2023-06-23 | — | — | CN | claimed |
| CN-116323614-A | Thioate derivatives of RABEXIMOD for the treatment of inflammatory and autoimmune disorders | 维洛诺瓦医药公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116323614-A | Thioate derivatives of RABEXIMOD for the treatment of inflammatory and autoimmune disorders | 维洛诺瓦医药公司 | 2023-06-23 | — | — | CN | disclosed |