Methane

Methane

SCHEMBL29028809

C.Nc1ccc(-c2ccc(N)c(C(=O)O)c2C(=O)O)cc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.41
KMT2A Q03164 3/20 0.41
GFER P55789 2/20 0.41
RXFP1 Q9HBX9 1/20 0.41
TDP1 Q9NUW8 5/20 0.40
MAPT P10636 4/20 0.40
RECQL P46063 3/20 0.40
POLB P06746 2/20 0.40
MEN1 O00255 2/20 0.40
THRB P10828 2/20 0.40
USP2 O75604 1/20 0.40
PKM P14618 1/20 0.40
APEX1 P27695 1/20 0.40
BLM P54132 1/20 0.40
MCL1 Q07820 1/20 0.40
PTPN1 P18031 3/20 0.37
MMP2 P08253 1/20 0.37
MMP3 P08254 1/20 0.37
MMP9 P14780 1/20 0.37
ALPL P05186 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9001554 0.98 KDM4E (0.42) KDM4EKMT2AGFERRXFP1TDP1
SCHEMBL28423399 0.85 ALDH1A1 (0.45) KDM4EKMT2AGFERRXFP1MAPT
SCHEMBL2929950 0.78 MAPT (0.38) KDM4EKMT2AGFERRXFP1TDP1
SCHEMBL29249187 0.77 MCL1 (0.47) KDM4EKMT2AGFERRXFP1TDP1
SCHEMBL5060828 0.77 MAPT (0.44) KMT2ATDP1MAPTPOLBMEN1
SCHEMBL3822164 0.77 KMT2A (0.48) KDM4EKMT2AGFERRXFP1TDP1
SCHEMBL31348929 0.77 KMT2A (0.48) KDM4EKMT2AGFERRXFP1TDP1
SCHEMBL29249197 0.76 ALDH1A1 (0.43) KDM4EKMT2AGFERRXFP1TDP1
SCHEMBL8154088 0.75 ALDH1A1 (0.42) KDM4EKMT2AGFERRXFP1TDP1
SCHEMBL28212637 0.75 MAOA (0.43) KMT2AGFERTDP1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112996664-B Polyimide composite film with excellent dielectric properties and preparation method thereof 聚酰亚胺先端材料有限公司 2023-08-08 CN claimed
CN-112867753-B Thick polyimide film with improved surface quality and method for producing same 聚酰亚胺先端材料有限公司 2023-07-07 CN claimed
CN-114072451-B Polyamic acid composition, method for preparing the same, and polyimide containing the same PI尖端素材株式会社 2024-07-02 CN disclosed
CN-114174422-B Resin composition and use thereof DIC株式会社 2024-04-30 CN disclosed
CN-116648475-A Polyamic acid composition and polyimide containing same PI尖端素材株式会社 2023-08-25 CN disclosed
CN-116568736-A Polyamic acid composition and polyimide containing same PI尖端素材株式会社 2023-08-08 CN disclosed
CN-116568735-A Polyamic acid composition and polyimide containing same PI尖端素材株式会社 2023-08-08 CN disclosed
CN-112996664-B Polyimide composite film with excellent dielectric properties and preparation method thereof 聚酰亚胺先端材料有限公司 2023-08-08 CN disclosed
CN-116529294-A Polyamic acid composition and polyimide containing same PI尖端素材株式会社 2023-08-01 CN disclosed
CN-116438257-A Polyamic acid composition and polyimide containing same PI尖端素材株式会社 2023-07-14 CN disclosed