Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3789904 | 0.84 | THRB (0.39) | MAPTNPC1RAB9APRKCZTDP1 | |
| SCHEMBL27842733 | 0.79 | THRB (0.47) | MAPTNPC1RAB9ATDP1ALDH1A1 | |
| SCHEMBL9001554 | 0.79 | KDM4E (0.42) | MAPTNPC1RAB9APRKCZTDP1 | |
| Methane SCHEMBL29028809 | 0.78 | KDM4E (0.41) | MAPTNPC1RAB9APRKCZTDP1 | |
| SCHEMBL9705201 | 0.77 | ALDH1A1 (0.47) | MAPTRAB9APRKCZALDH1A1TP53 | |
| SCHEMBL5060828 | 0.74 | MAPT (0.44) | MAPTRAB9ATDP1ALDH1A1CYP3A4 | |
| SCHEMBL29229205 | 0.74 | PRKCZ (0.62) | MAPTNPC1RAB9APRKCZALDH1A1 | |
| SCHEMBL3790376 | 0.73 | PRKCI (0.50) | MAPTNPC1RAB9ATDP1CYP3A4 | |
| SCHEMBL3787112 | 0.73 | MAPT (0.49) | MAPTNPC1RAB9AHSD17B1SMN1; SMN2 | |
| SCHEMBL3785357 | 0.72 | MAPT (0.41) | MAPTNPC1RAB9ATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106631866-A | Synthesis process of medical and chemical intermediate 3,3'-dinitro-4,4'-diacetylbiphenyldiamine | 徐州诺克非医药科技有限公司 | 2017-05-10 | — | — | CN | claimed |
| CN-106631866-B | A kind of synthesis technology of pharmaceutical-chemical intermediate 3,3 '-dinitro -4,4 '-diacetyl benzidine | 湖南奥朗特医疗器械有限公司 | 2018-06-19 | — | — | CN | disclosed |
| CN-106631866-B | A kind of synthesis technology of pharmaceutical-chemical intermediate 3,3 '-dinitro -4,4 '-diacetyl benzidine | 湖南奥朗特医疗器械有限公司 | 2018-06-19 | — | — | CN | disclosed |
| CN-106631866-A | Synthesis process of medical and chemical intermediate 3,3'-dinitro-4,4'-diacetylbiphenyldiamine | 徐州诺克非医药科技有限公司 | 2017-05-10 | — | — | CN | disclosed |
| EP-1730102-B1 | A NOVEL CATALYTIC PROCESS FOR THE PRODUCTION OF 3,3 , 4,4'-TETRAMINOBIPHENYL | COUNCIL SCIENT IND RES (IN) | 2010-09-22 | — | — | EP | disclosed |
| EP-1727781-B1 | PROCESS FOR THE PREPARATION OF HIGH QUALITY 3,3',4,4'-TETRAMINOBIPHENYL | COUNCIL SCIENT IND RES (IN) | 2009-05-06 | — | — | EP | disclosed |
| EP-1730102-A1 | A NOVEL CATALYTIC PROCESS FOR THE PRODUCTION OF 3,3 , 4,4'-TETRAMINOBIPHENYL | Council of Scientific and Industrial Research (IN) | 2006-12-13 | — | — | EP | disclosed |
| EP-1727781-A1 | PROCESS FOR THE PREPARATION OF HIGH QUALITY 3,3',4,4'-TETRAMINOBIPHENYL | Council of Scientific and Industrial Research (IN) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005092839-A1 | A NOVEL CATALYTIC PROCESS FOR THE PRODUCTION OF 3,3', 4,4'-TETRAMINOBIPHENYL | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-10-06 | — | — | WO | disclosed |
| WO-2005063679-A1 | PROCESS FOR THE PREPARATION OF HIGH QUALITY 3,3',4,4'-TETRAMINOBIPHENYL | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2005-07-14 | — | — | WO | disclosed |
| US-6835854-B1 | Oxidation of 3,3'-dichloro 4,4'-diaminobiphenyl (DCB), ammonolysis of the resulting 3,3'-dichloro-4,4'-dinitrobiphenyl (DCDNB) and reduction of 3,3'-diamino-4,4'-dinitrobiphenyl and treating with an alkali | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-12-28 | — | — | US | disclosed |