Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9345089 | 0.86 | FDPS (0.46) | FDPSTSHRKMT2ACYP2D6MEN1 | |
| SCHEMBL12293992 | 0.84 | HRH4 (0.37) | THRBTSHR | |
| SCHEMBL6050108 | 0.83 | FDPS (0.44) | FDPSTSHRKMT2ACYP2D6MEN1 | |
| Hydrochloric Acid SCHEMBL7423281 | 0.81 | FDPS (0.42) | FDPSTSHRKMT2ACYP2D6MEN1 | |
| SCHEMBL29234290 | 0.81 | KMT2A (0.37) | FDPSTSHRKMT2ACYP2D6MEN1 | |
| SCHEMBL17308699 | 0.78 | ALDH1A1 (0.49) | THRBFDPSTSHRALDH1A1CHRM3 | |
| SCHEMBL22567313 | 0.78 | THRB (0.46) | THRBTSHRALDH1A1CHRM2CHRM4 | |
| SCHEMBL1394651 | 0.78 | THRB (0.46) | THRBTSHRALDH1A1CHRM2CHRM4 | |
| SCHEMBL16874410 | 0.78 | THRB (0.46) | THRBTSHRALDH1A1CHRM2CHRM4 | |
| SCHEMBL5479801 | 0.78 | THRB (0.40) | THRBTSHRALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116333190-B | Multiple-response prodrug polymer, preparation method and application | 郑州大学 | 2024-05-24 | — | — | CN | claimed |
| CN-116333190-A | Multiple-response prodrug polymer, preparation method and application | 郑州大学 | 2023-06-27 | — | — | CN | claimed |
| CN-116333190-B | Multiple-response prodrug polymer, preparation method and application | 郑州大学 | 2024-05-24 | — | — | CN | disclosed |
| CN-116333190-A | Multiple-response prodrug polymer, preparation method and application | 郑州大学 | 2023-06-27 | — | — | CN | disclosed |