SCHEMBL29028841

SCHEMBL29028841

C1=C(c2cc3ccccc3o2)CCCC1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.46
NPC1 O15118 5/20 0.44
RAB9A P51151 5/20 0.44
HSD17B10 Q99714 3/20 0.44
KDM4E B2RXH2 3/20 0.44
ALDH1A1 P00352 3/20 0.44
HTT P42858 1/20 0.44
MAOB P27338 4/20 0.44
MAOA P21397 3/20 0.44
METAP2 P50579 1/20 0.43
ADRA2A P08913 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
HPGD P15428 1/20 0.42
ADRA2B P18089 1/20 0.42
ADRA2C P18825 1/20 0.42
NISCH Q9Y2I1 1/20 0.42
ALOX5 P09917 1/20 0.41
MAPT P10636 3/20 0.41
ELANE P08246 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2085345 0.95 MAOB (0.45) TDP1NPC1RAB9AHSD17B10KDM4E
SCHEMBL11112466 0.75 MAOB (0.49) NPC1RAB9AHSD17B10KDM4EALDH1A1
SCHEMBL4148268 0.74 PRKDC (0.44) TDP1NPC1RAB9AHSD17B10KDM4E
SCHEMBL5585118 0.74 MAOB (0.47) NPC1RAB9AHSD17B10KDM4EALDH1A1
SCHEMBL4357694 0.74 SIGMAR1 (0.50) NPC1RAB9AHSD17B10KDM4EALDH1A1
SCHEMBL30036439 0.73 MAOB (0.63) TDP1NPC1RAB9AHSD17B10KDM4E
SCHEMBL103158 0.73 MAOB (0.63) TDP1NPC1RAB9AHSD17B10KDM4E
SCHEMBL10900184 0.72 RAB9A (0.46) NPC1RAB9AKDM4EALDH1A1MAOB
SCHEMBL10901794 0.72 NPC1 (0.46) NPC1RAB9ACYP2D6HPGDMAPT
SCHEMBL2150499 0.69 MAOB (0.59) TDP1NPC1RAB9AHSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110386909-B Method for synthesizing benzofuran derivative through copper-free ligand-free palladium catalyst 中国科学院青岛生物能源与过程研究所 2023-07-07 CN disclosed