Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28652589 | 0.86 | HDAC6 (0.37) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL6512340 | 0.86 | HDAC6 (0.37) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL7024160 | 0.72 | HDAC6 (0.41) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL20287503 | 0.70 | DGAT1 (0.39) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL9873641 | 0.70 | HDAC6 (0.36) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL2703822 | 0.70 | HDAC6 (0.33) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL3361720 | 0.68 | HDAC6 (0.35) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL2552626 | 0.68 | HDAC6 (0.35) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL28783743 | 0.68 | HDAC6 (0.35) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL16998486 | 0.68 | CTSD (0.36) | HDAC6HDAC1HDAC2DGAT1CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116171154-A | Modulators of cystic fibrosis transmembrane conductance regulator | 弗特克斯药品有限公司 | 2023-05-26 | — | — | CN | disclosed |