Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cinnamaldehyde. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.75 |
| ▸ | LMNA | P02545 | 3/20 | 0.75 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.75 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.75 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CDK4 | P11802 | 5/20 | 0.50 |
| ▸ | CCND1 | P24385 | 5/20 | 0.50 |
| ▸ | CCNB2 | O95067 | 4/20 | 0.50 |
| ▸ | CDK1 | P06493 | 4/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.50 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cinnamaldehyde SCHEMBL6061954 | 1.00 | ALDH1A1 (0.75) | ALDH1A1LMNATRPA1ALOX5MAPK1 | |
| Cinnamaldehyde SCHEMBL26923210 | 1.00 | ALDH1A1 (0.75) | ALDH1A1LMNATRPA1ALOX5MAPK1 | |
| Cinnamic Aldehyde SCHEMBL3340838 | 1.00 | ALDH1A1 (0.75) | ALDH1A1LMNATRPA1ALOX5MAPK1 | |
| Cinnamaldehyde SCHEMBL28719829 | 0.92 | LMNA (0.69) | ALDH1A1LMNATRPA1ALOX5MAPK1 | |
| Cinnamaldehyde SCHEMBL28719830 | 0.92 | LMNA (0.69) | ALDH1A1LMNATRPA1ALOX5MAPK1 | |
| Cinnamaldehyde SCHEMBL22729219 | 0.89 | ALDH1A1 (0.78) | ALDH1A1LMNATRPA1ALOX5MAPK1 | |
| Cinnamaldehyde SCHEMBL22729220 | 0.89 | ALDH1A1 (0.78) | ALDH1A1LMNATRPA1ALOX5MAPK1 | |
| Cinnamic Aldehyde SCHEMBL22729218 | 0.89 | ALDH1A1 (0.78) | ALDH1A1LMNATRPA1ALOX5MAPK1 | |
| Cinnamaldehyde SCHEMBL29206157 | 0.89 | ALDH1A1 (0.86) | ALDH1A1LMNATRPA1ALOX5MAPK1 | |
| Cinnamaldehyde SCHEMBL29206156 | 0.89 | ALDH1A1 (0.86) | ALDH1A1LMNATRPA1ALOX5MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116138307-B | Controlled-release green fruit and vegetable preservative material and preparation method and application thereof | 广东省农业科学院蚕业与农产品加工研究所 | 2024-03-19 | — | — | CN | disclosed |
| CN-116138307-A | Controlled-release green fruit and vegetable preservative material and preparation method and application thereof | 广东省农业科学院蚕业与农产品加工研究所 | 2023-05-23 | — | — | CN | disclosed |