Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29029071 | 0.90 | ALDH1A1 (0.49) | ALDH1A1TSHRKDM4ECYP19A1LMNA | |
| SCHEMBL29471221 | 0.87 | ALDH1A1 (0.47) | ALDH1A1TSHRKDM4ECYP19A1LMNA | |
| SCHEMBL29029059 | 0.83 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM4ECYP19A1LMNA | |
| SCHEMBL29029090 | 0.82 | TSHR (0.49) | ALDH1A1TSHRKDM4ECYP19A1LMNA | |
| SCHEMBL9980399 | 0.79 | ALDH1A1 (0.59) | ALDH1A1KDM4ELMNASMN1; SMN2HTT | |
| SCHEMBL26547989 | 0.79 | KDM4E (0.60) | ALDH1A1TSHRKDM4ECYP19A1LMNA | |
| SCHEMBL30480910 | 0.78 | ALDH3A1 (0.60) | ALDH1A1TSHRKDM4ECYP19A1LMNA | |
| SCHEMBL4911967 | 0.73 | ALDH1A1 (0.70) | ALDH1A1TSHRCYP19A1LMNASMN1; SMN2 | |
| SCHEMBL28156680 | 0.73 | MEN1 (0.71) | ALDH1A1TSHRCYP19A1GAAPOLB | |
| SCHEMBL11637929 | 0.72 | NPC1 (0.59) | ALDH1A1TSHRCYP19A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4210683-A1 | HETEROCYCLIC COMPOUNDS AS CBP/EP300 BROMODOMAIN INHIBITORS | Aurigene Oncology Limited (IN) | 2023-07-19 | — | — | EP | disclosed |
| CN-116368128-A | Heterocyclic compounds as CBP/EP300 bromodomain inhibitors | 奥瑞基尼肿瘤有限公司 | 2023-06-30 | — | — | CN | disclosed |
| WO-2022053967-A1 | HETEROCYCLIC COMPOUNDS AS CBP/EP300 BROMODOMAIN INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2022-03-17 | — | — | WO | disclosed |