SCHEMBL29029663

SCHEMBL29029663

CCC(C(N)=O)(C(=O)c1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 8/20 0.45
MAPT P10636 3/20 0.45
CYP2C19 P33261 3/20 0.45
CYP3A4 P08684 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
TSHR P16473 2/20 0.45
POLB P06746 1/20 0.45
PARP1 P09874 1/20 0.45
RECQL P46063 1/20 0.45
BLM P54132 1/20 0.45
PMP22 Q01453 1/20 0.45
HSD17B10 Q99714 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
CES2 O00748 5/20 0.42
KMT2A Q03164 2/20 0.42
SRC P12931 1/20 0.42
CTNNB1 P35222 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
LMNA P02545 1/20 0.39
HPGD P15428 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27714041 0.88 CES1 (0.52) CES1MAPTCYP2C19CYP3A4TDP1
SCHEMBL29029684 0.84 CES1 (0.48) CES1MAPTCYP2C19CYP3A4TDP1
SCHEMBL28304897 0.81 CTNNB1 (0.51) CES1MAPTCYP2C19CYP3A4TDP1
SCHEMBL29035571 0.78 CES1 (0.44) CES1MAPTCYP2C19CYP3A4TDP1
SCHEMBL29029673 0.77 PIN1 (0.50) CES1MAPTTSHRPOLBRECQL
SCHEMBL9631851 0.76 CES1 (0.48) CES1MAPTCYP2C19CYP3A4TDP1
SCHEMBL28167005 0.76 CES1 (0.48) CES1MAPTCYP2C19CYP3A4TDP1
SCHEMBL8459655 0.75 CTNNB1 (0.61) CES1MAPTCYP2C19CYP3A4TDP1
SCHEMBL5031584 0.75 CES1 (0.52) CES1MAPTCYP2C19CYP3A4TDP1
SCHEMBL9076470 0.74 CES1 (0.47) CES1MAPTCYP2C19CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116219085-B Synthetic tanning agent containing multifunctional structure and preparation method and application thereof 南京工业大学 2024-03-15 CN disclosed
CN-116219085-A Synthetic tanning agent containing multifunctional structure and preparation method and application thereof 南京工业大学 2023-06-06 CN disclosed