SCHEMBL29029684

SCHEMBL29029684

CCC(C(=O)O)(C(=O)c1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 10/20 0.48
CES2 O00748 7/20 0.45
SRC P12931 1/20 0.44
CTNNB1 P35222 1/20 0.43
HPGD P15428 2/20 0.41
MAPK1 P28482 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
CYP3A4 P08684 1/20 0.41
MAPT P10636 1/20 0.41
ALOX15 P16050 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
LMNA P02545 1/20 0.41
ALDH1A1 P00352 3/20 0.41
TSHR P16473 2/20 0.41
DAO P14920 1/20 0.41
NAPRT Q6XQN6 1/20 0.41
CYP1A2 P05177 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27714041 0.91 CES1 (0.52) CES1CES2SRCCTNNB1HPGD
SCHEMBL29035571 0.89 CES1 (0.44) CES1CES2SRCCTNNB1HPGD
SCHEMBL29029663 0.84 CES1 (0.45) CES1CES2SRCCTNNB1HPGD
SCHEMBL29029673 0.80 PIN1 (0.50) CES1SRCMAPK1MEN1MAPT
SCHEMBL10887175 0.79 CES1 (0.48) CES1CES2SRCHPGDMAPK1
SCHEMBL7088571 0.79 CTNNB1 (0.54) CES1CES2SRCCTNNB1HPGD
SCHEMBL8459655 0.78 CTNNB1 (0.61) CES1CES2SRCCTNNB1HPGD
SCHEMBL5031584 0.78 CES1 (0.52) CES1CES2SRCCTNNB1HPGD
SCHEMBL8679764 0.78 CES1 (0.52) CES1CES2SRCCTNNB1HPGD
SCHEMBL4808857 0.78 CES1 (0.47) CES1CES2SRCCTNNB1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116219085-B Synthetic tanning agent containing multifunctional structure and preparation method and application thereof 南京工业大学 2024-03-15 CN disclosed
CN-116970746-A Synthetic tanning agent containing hexabasic carbonyl and preparation method and application thereof 南京工业大学 2023-10-31 CN disclosed
CN-116219085-A Synthetic tanning agent containing multifunctional structure and preparation method and application thereof 南京工业大学 2023-06-06 CN disclosed